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Clínica Las Condes. Dirección Académica. DA-CLC In adults, metformin promotes weight loss and prevents the development of type 2 diabetes mellitus DM2. However, these effects have not been demonstrated in adolescents at risk for DM2. Objective: To analyze the anthropometric and metabolic impact of metformin in obese adolescents at risk for DM2.
Patients and Methods: A double-blind, placebo-controlled study was conducted in 19 obese female adolescents at risk for DM2. A structured lifestyle intervention with nutritional and exercise education and motivational support was assessed over 3 month with adelgazar corriendo sin dieta additional follow up period of 3 months. Results: Metformin treated group showed a significant reduction in weight and body mass index BMI compared with placebo group.
No improvement in the metabolic risk profile was showed in any group. Conclusion: In this study, metformin therapy in combination with a lifestyle intervention helps to reduce weight and BMI in obese adolescent females at risk for DM2, compared to metformin 500 mg can you lose weight on it and placebo intervention.
AU En adultos, se ha demostrado que la metformina favorece la reducción de peso y previene el desarrollo de Diabetes Mellitus tipo 2 DM2. Objetivo: Analizar el impacto antropométrico y metabólico de la metformina en adolescentes obesas con riesgo de DM2. La dieta de reinicio de Keto Un enfoque práctico para la pérdida de peso saludable..